COMPARATIVE ANALYSIS OF THE EFFECT OF LOCAL OZONE THERAPY ON THE ADAPTATION PROCESS TO COMPLETE REMOVABLE DENTURES IN ELDERLY PATIENTS
Keywords:
complete edentulism; complete removable dentures; elderly patients; local ozone therapy; ozonated olive oil; Ambjørnsen index; mixed saliva; pH; viscosity; oral microflora; Candida spp.; adaptation; oral hygiene.Abstract
The clinical and laboratory effectiveness of local ozone therapy (ozonated olive oil) during the adaptation period to complete removable acrylic dentures in elderly completely edentulous patients was comparatively evaluated. Patients were divided into a control group (conventional prosthetic treatment) and a comparison group (conventional prosthetics combined with local ozone therapy). Over a follow-up period of 14 days to 6 months, denture hygiene (Ambjørnsen index), gingival inflammation, subjective complaints, mixed saliva parameters (secretion rate, pH, viscosity), oral microflora, and Candida spp. colonization were analyzed. In patients treated with conventional prosthetics, denture hygiene deteriorated after two weeks, accompanied by more pronounced signs of microbial imbalance. In contrast, patients receiving local ozone therapy demonstrated better preservation of hygiene indices, absence of Candida colonization, enhanced epithelial regeneration, and a more rapid reduction of subjective complaints. Local ozone therapy was assessed as an effective pathogenetic method, reducing the adaptation period to complete removable dentures by approximately 30%.
References
1. Azarpazhooh A., Limeback H. The application of ozone in dentistry: a systematic review // Journal of Dentistry. – 2008. – Vol. 36, No. 2. – P. 104–116.
2. Baysan A., Lynch E. The use of ozone in dentistry and medicine // Primary Dental Care. – 2004. – Vol. 11, No. 2. – P. 37–41.
3. Budtz-Jørgensen E. Prosthodontics for the elderly: diagnosis and treatment. – Chicago: Quintessence Publishing, 1999. – 432 p.
4. Carlsson G.E., Omar R. The future of complete dentures in oral rehabilitation // Journal of Oral Rehabilitation. – 2010. – Vol. 37, No. 2. – P. 143–156.
5. Coco B.J., Bagg J., Cross L.J. et al. Mixed Candida albicans and Candida glabrata populations in the oral cavity of denture wearers // Oral Microbiology and Immunology. – 2008. – Vol. 23. – P. 377–383.
6. Dawes C., Pedersen A.M., Villa A. et al. The functions of human saliva: a review sponsored by the World Workshop on Oral Medicine VI // Archives of Oral Biology. – 2015. – Vol. 60, No. 6. – P. 863–874.
7. GBD 2019 Oral Disorders Collaborators. Global prevalence and incidence of oral conditions for 195 countries, 1990–2019 // Journal of Dental Research. – 2020. – Vol. 99, No. 4. – P. 362–373.
8. Gendreau L., Loewy Z.G. Epidemiology and etiology of denture stomatitis // Journal of Prosthodontics. – 2011. – Vol. 20, No. 4. – P. 251–260.
9. Müller F., Naharro M., Carlsson G.E. What are the prevalence and incidence of tooth loss in the adult and elderly population in Europe? // Clinical Oral Implants Research. – 2007. – Vol. 18, Suppl. 3. – P. 2–14.
10. Nagayoshi M., Fukuizumi T., Kitamura C. et al. Efficacy of ozone on survival and permeability of oral microorganisms // Oral Microbiology and Immunology. – 2004. – Vol. 19. – P. 240–246.
11. Preshaw P.M., Hennequin-Hoenderdos N.L., Heasman P.A. et al. Periodontitis and diabetes: a two-way relationship // Diabetologia. – 2011. – Vol. 55. – P. 21–31.
12. Sechi L.A., Lezcano I., Nunez N. et al. Antibacterial activity of ozonized sunflower oil (Oleozon) // Journal of Applied Microbiology. – 2001. – Vol. 90. – P. 279–284.
13. Turner M.D., Ship J.A. Dry mouth and its effects on the oral health of elderly people // Journal of the American Dental Association. – 2007. – Vol. 138. – P. 15S–20S.
14. World Health Organization. Oral health. – Geneva: WHO Press, 2012. – 64 p.
